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◆ Associate Professor |
Name: Ge Zhang
Academic qualifications:
1990.9-1995.7 B. Med. ShanghaiUniversity of Chinese Medicine, Shanghai, China
1997.9-2000.7 M. Med. Institute of Orthopaedics &Traumatology, Shanghai University
of Chinese Medicine, China
2000.9-2003.7 M.D. Institute of Orthopaedics & Traumatology, Shanghai University of
Chinese Medicine & Deparment of Orthopaedics & Traumatology,
The Chinese University of Hong Kong
Previous academic positions held:
1995.8-2000.11 Resident Institute of Orthopaedics &Traumatology, Shu
Guang Hospital,Shanghai University of Chinese
Medicine
2000.12-2004.2 Physician-in-Charge Institute of Orthopaedics &Traumatology, Shu
Guang Hospital, ShanghaiUniversity of Chinese
Medicine
2004.3-2007.60 Postdoctoral Research Department ofOrthopaedics & Traumatology, The
Fellow Chinese University of HongKong
2007.7-2012.80 Research Assistant Department of Orthopaedics & Traumatology, The
Professor Chinese Universityof Hong Kong
Present academic position:
2012.9- Associate Professor Ge Zhang’s Lab (www.gezhanglab.com),Institute for
Advancing Translational Medicine in Bone & Joint Diseases,
Hong Kong BaptistUniversity & Teaching Division, School
of Chinese Medicine, Hong Kong Baptist University
Previous relevant research work:
Technical expertise Bone bio-imaging, Bone histomorphometry,Bone biology, Bone
biomechanics
Research area Molecular understandings and RNAi-based & phytotherapy-based
translationalresearch in osteoporosis,osteonecrosis, osteoarthritis,
rheumatoid arthritis and facture repair
Publication Records:
3 Theses; 9 Book Chapters; 106 SCIPapers;Sum of the Times cited (excluding self-citation): 220; h-index: 9
Ten Representative publications in the past ten years
1. WangX, Guo B, …, Zhang G (Corresponding Author), Li Y(Corresponding Author). miR-
214targets ATF4 to inhibit bone formation. NatMed. 2013 Jan;19(1):93-100
2. Zhang G (Corresponding Author), Guo B, Wu H, Tang T, Zhang BT, …,Zhang L
(Corresponding Author), Qin L (Corresponding Author). A deliverysystemtargeting
bone formation surfaces to facilitate RNAi-based anabolictherapy. NatMed.
2012 Jan 29;18(2):307-14
3. XieXH, Wang XL, He YX, Liu Z, Sheng H, Zhang G (CorrespondingAuthor), Qin L
(Corresponding Author).Promotion of bone repair byimplantation of cryopreserved bone
marrow-derivedmononuclear cells in a rabbitmodel of steroid-associated osteonecrosis.
Arthritis Rheum.2012May;64(5):1562-71
4. HeYX, Liu Z, Pan XH, Tang T, Guo BS, Zheng LZ, Xie XH, Wang XL, Lee KM, LiG, CaoYP, Wei
L, Chen Y, Yang ZJ, Hung LK, Qin L, Zhang G (CorrespondingAuthor). Deletion of estrogen
receptor betaaccelerates early stage ofbone healing in a mouse osteotomy model.
Osteoporosis Int.2012Jan;23(1):377-89.
5. Zhang G,Sheng H, et al. Continuous occurrenceof both insufficient neovascularizationand
elevated vascular permeability inrabbit proximal femur during inadequaterepair of steroid-
associatedosteonecrotic lesions.ArthritisRheum.2009 Oct;60(10):2966-77.
6. Zhang G,Wang XL, Sheng H, et al. Constitutionalflavonoids derived from Epimediumdose-
dependently reduce incidence ofsteroid-associated osteonecrosis not viadirect action by
themselves onpotential cellular targets. PlosOne 2009; 4: e6419
7. Zhang G, Qin L, et al. A Novel Semisynthesized SmallMoleculeIcaritin Reduces Incidence of
Steroid-associated Osteonecrosis withInhibitionof both Thrombosis and Lipid-deposition in a
Dose-dependent Manner.Bone2009; 44:345-56
8. Zhang G, QinL, Shi Y. Epimedium-derivedphytoestrogen flavonoids exert beneficial effect
on preventing bone loss in latepostmenopausal women: a 24-month randomized,double-blind
and placebo-controlledtrial. J Bone Miner Res. 2007Jul;22(7):1072-9.
9. Zhang G,Qin L, et al. Flavonoids derived fromherbal Epimedium Brevicornum Maxim
prevent OVX-induced osteoporosis in ratsindependent of its enhancement in
intestinalcalcium absorption. Bone.2006 Jun;38(6):818-25.
10.Zhang G (Corresponding Author), et al. A comparative study between axialcompression
andlateral fall configuration tested in a rat proximal femurmodel. Clin Biomech (Bristol,
Avon). 2005 Aug;20(7):729-35.