◆ Associate Professor
◆ Executive Director of Institute for Advancing Translational Medicine in Bone & Joint Diseases
◆ Major: Clinical Orthopedics & Musculoskeletal Science
◆ E-mail: zhangge@hkbu.edu.hk

Name: Ge Zhang

Academic qualifications:

1990.9-1995.7  B. Med.   ShanghaiUniversity of Chinese Medicine, Shanghai, China

1997.9-2000.7  M. Med.  Institute of Orthopaedics &Traumatology, Shanghai University

                                   of Chinese Medicine, China

2000.9-2003.7  M.D.       Institute of Orthopaedics &  Traumatology, Shanghai University of

                                  Chinese Medicine & Deparment of  Orthopaedics & Traumatology,

                                  The Chinese University of Hong Kong


Previous academic positions held:

1995.8-2000.11  Resident                      Institute  of Orthopaedics &Traumatology, Shu

                                                        Guang Hospital,Shanghai University of Chinese

                                                        Medicine

2000.12-2004.2  Physician-in-Charge       Institute  of Orthopaedics &Traumatology, Shu

                                                        Guang Hospital, ShanghaiUniversity  of Chinese

                                                        Medicine

2004.3-2007.60  Postdoctoral Research    Department  ofOrthopaedics & Traumatology, The

                       Fellow                         Chinese University of HongKong

2007.7-2012.80  Research Assistant        Department of Orthopaedics & Traumatology, The

                       Professor                     Chinese Universityof Hong Kong


Present academic position:

2012.9-  Associate Professor   Ge  Zhang’s Lab (www.gezhanglab.com),Institute  for

                                         Advancing Translational Medicine in Bone & Joint Diseases,

                                         Hong Kong  BaptistUniversity & Teaching Division, School

                                         of Chinese Medicine, Hong  Kong Baptist University  


Previous relevant research work:

Technical expertise   Bone  bio-imaging, Bone histomorphometry,Bone biology, Bone

                             biomechanics

Research area          Molecular understandings and RNAi-based & phytotherapy-based

                             translationalresearch in osteoporosis,osteonecrosis, osteoarthritis,

                             rheumatoid arthritis and  facture repair


Publication Records:

3 Theses; 9 Book Chapters; 106 SCIPapers;Sum of the Times cited (excluding self-citation): 220; h-index: 9


Ten Representative publications in the past ten years

1.  WangX, Guo B, …, Zhang G (Corresponding Author), Li Y(Corresponding Author). miR-

    214targets ATF4 to inhibit bone formation. NatMed. 2013 Jan;19(1):93-100

2.  Zhang G (Corresponding Author), Guo B, Wu H, Tang T, Zhang BT, …,Zhang L

    (Corresponding Author), Qin L (Corresponding Author). A deliverysystemtargeting

    bone formation surfaces to facilitate RNAi-based anabolictherapy. NatMed.

    2012 Jan 29;18(2):307-14

3.  XieXH, Wang XL, He YX, Liu Z, Sheng H, Zhang G (CorrespondingAuthor), Qin L

    (Corresponding Author).Promotion of bone repair byimplantation of cryopreserved bone

    marrow-derivedmononuclear cells in a rabbitmodel of steroid-associated osteonecrosis.

     Arthritis Rheum.2012May;64(5):1562-71

4.  HeYX, Liu Z, Pan XH, Tang T, Guo BS, Zheng LZ, Xie XH, Wang XL, Lee KM, LiG, CaoYP, Wei

    L, Chen Y, Yang ZJ, Hung LK, Qin L, Zhang G (CorrespondingAuthor). Deletion of estrogen

    receptor betaaccelerates early stage ofbone healing in a mouse osteotomy model.

     Osteoporosis Int.2012Jan;23(1):377-89.

5.  Zhang G,Sheng H, et al. Continuous occurrenceof both insufficient neovascularizationand

    elevated vascular permeability inrabbit proximal femur during inadequaterepair of steroid-

    associatedosteonecrotic lesions.ArthritisRheum.2009 Oct;60(10):2966-77.

6.  Zhang G,Wang XL, Sheng H, et al. Constitutionalflavonoids derived from Epimediumdose-

    dependently reduce incidence ofsteroid-associated osteonecrosis not viadirect action by

    themselves onpotential cellular targets. PlosOne 2009; 4: e6419

7.  Zhang G, Qin L, et al. A Novel Semisynthesized SmallMoleculeIcaritin Reduces Incidence of

    Steroid-associated Osteonecrosis withInhibitionof both Thrombosis and Lipid-deposition in a

    Dose-dependent Manner.Bone2009; 44:345-56

8.  Zhang G, QinL, Shi Y. Epimedium-derivedphytoestrogen flavonoids exert beneficial effect

    on preventing bone loss in latepostmenopausal women: a 24-month randomized,double-blind

    and placebo-controlledtrial. J Bone Miner Res. 2007Jul;22(7):1072-9.

9.  Zhang G,Qin L, et al. Flavonoids derived fromherbal Epimedium Brevicornum Maxim

    prevent OVX-induced osteoporosis in ratsindependent of its enhancement in

    intestinalcalcium absorption. Bone.2006 Jun;38(6):818-25.

10.Zhang G (Corresponding Author), et al. A comparative study between axialcompression

    andlateral fall configuration tested in a rat proximal femurmodel. Clin Biomech (Bristol,

      Avon). 2005 Aug;20(7):729-35.


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