Name: Zhaoxiang Bian

Academic qualifications:

1984.9-1988.7  B. Med.   Nanjing University of Chinese  Medicine, P. R. CHINA

1988.9-1991.7  M. Med.   Beijing University of Traditional  Chinese Medicine, P. R. CHINA

1991.9-1994.7  Ph.D.      Guangzhou University of Traditional Chinese  Medicine, P. R. CHINA

Previousacademic positions held:

1994.7-1995.11  Lecturer                  Institute of Digestive Diseases Guangzhou

                                                    University of  Traditional ChineseMedicine,

                                                    P. R. China                                

1996.4-2000.1   Associate Professor    Institute  of Digestive DiseasesGuangzhou

                                                    University of  Traditional Chinese Medicine,

                                                    P. R. China

2000.2-2001.4   Associate Professor   Guangzhou University of Traditional  Chinese

                                                    Medicine, P. R. China

2001.5-2010.8   Assistant Professor    Clinical Divison, School  of Chinese Medicine,

                      and Director              Hong Kong Baptist University, Hong Kong

Present academic position:

2010.9-  Professor and Director  Clinical Divison, School  of Chinese Medicine, Hong

                                            Kong Baptist University,  Hong Kong

Previousrelevant research work:

Research area   Mechanism of development of irritable bowel syndrome, inflammatory

                      bowel disease, and  colorectal cancer; Therapeutic effectsof Traditi

                      onal Chinese medicine and  their mechanism for digestivediseases

Publication records:

3Theses;14 Book Chapters; 62 SCI Papers; Sum of the Times cited (excludingself-citation): 385;h-index: 12

Ten Representative publications in the past ten years:

1.  Bian ZX*.Novel insights about the mechanismof visceral hypersensitivity in maternally

     separated rats. Neurogastroent& Motil, 2012; 24(7): 593-6.

2.  Zhang XJ, Choi FFK, Yan Z, Leung FP,Tan S, Lin SH, XuHX, Jia W, Sung JJY, Cai ZW,

      Bian ZX*.Metabolite profiling of plasma andurine from rats with TNBS-induced acutecolitis

     using UPLC-ESI-QTOF-MS-basedmetabonomics. FEBS J, 2012, 279: 2322–2331.

3.  Qin HY, Xiao HT, Leung FP, Wu JCY,Sung JJY, Xu HX, TongXD, Bian ZX*. JCM-16021, a

     Chinese herbal formula, attenuatedvisceral hyperalgesia in TNBS-induced post-

     inflammatory irritable bowelsyndrome rats through reducing colonic ECcell hyperplasia

     and serotonin availability. Evid.-basedComplement Altern. Med., 2012; 239638.

4.  Tsang SW, Zhao M, Wu J, Sung JJ, Bian ZX*. Nervegrowth factor-mediated neuronal

     plasticityin spinal cord contributes toneonatal maternal separation-induced visceral

     hypersensitivity in rats.Eur J Pain. 2012;16(4):463-72

5.  Luo JL, Qin HY, Wong CK, Tsang SY,Huang Y, Bian ZX*. EnhancedExcitability and

     Down-RegulatedVoltage-Gated Potassium Channels in Colonic DRG Neurons from

     Neonatal MaternalSeparation Rats.J Pain., 2011, 12(5): 600-9.

6.  Bian ZX*, Shang HC. CONSORT 2010 statement: updatedguidelines for reporting

     parallelgroup randomized trials.Ann InternMed., 2011, 154(4):290-1.

7.  Cheng CW, BianZX*, etal. Efficacy of a Chinese herbalproprietary medicine (Hemp

     SeedPill) for functional constipation.Am JGastroenterol., 2011,106(1):120-9.

8.  Bian ZX*, Qin HY, Tian SL, Qi SD. Combinedeffect of early life stress and acute stress

     oncolonic sensory and motor responses through serotonin pathways: differencesbetween

     proximal and distal coloninrats. Stress. 2011;14(4):448-58

9.  Zhang M, Leung FP, Huang Y, Bian ZX*. Increased colonic motility in arat model of

     irritable bowelsyndrome is associated with up-regulation of L-type calcium channels in

     colonic smooth muscle cells. Neurogastroent&Motil, 2010, 22(5): 162-70.

10. Zhang XJ, Chen HL, Li Z, Zhang HQ, XuHX, Sung JJ, Bian ZX*. Analgesic effect of

     paeoniflorin inrats with neonatal maternal separation-induced visceral hyperalgesia

     is mediated through adenosine A(1) receptor by inhibitingthe extracellular signal-

     regulated protein kinase (ERK) pathway. PharmacolBiochem Behav,2009, 94(1):88-97.